Chugai Pharmaceutical

The Japanese Roche subsidiary Chugai is halting clinical development of emugrobart (GYM329) for obesity after an interim analysis likely showed no clinically meaningful additional weight loss; the rights will now rest with Chugai. Roche had already removed emugrobart from programs for SMA and FSHD in March. Chugai is preparing a possible Phase III study in SMA and is examining an out‑licensing to third parties; the Roche share was briefly up about 1.15%. » More on finanzen.net

Chugai has received approval in Japan for the cancer test FoundationOne CDx as a companion diagnostic for the drug Tovorafenib. The test detects genetic alterations in tumor tissue, extending its indication to a total of nine cancer types. Chugai is thus strengthening its position in personalized cancer treatment; the stock fell 0.83 percent in Tokyo to ¥6,446. » More on finanzen.net

Chugai has submitted an approval application in Japan for Vamikibart to treat uveitic macular edema (UME). If approved, Vamikibart would be the first anti-IL-6 antibody therapy for this form of UME in Japan. The drug received orphan drug designation at the end of June. » More on finanzen.net