Quoin Pharmaceuticals ADR Aktie

Quoin Pharmaceuticals has submitted an IND application to the FDA for QRX003 to treat peeling skin syndrome (PSS) and plans to start a Phase 2 trial in the second half of 2026 pending regulatory approval. The application is supported by clinical observations from an ongoing pediatric study in which the first patient showed improvements in skin findings, sleep and quality of life over 15 months; QRX003 was well tolerated. The Phase 2 trial will aim to recruit six to eight pediatric and adult patients in the US and Europe; QRX003 therefore represents a second indication in addition to Netherton syndrome. Quoin also announced plans to clinically evaluate its topical rapamycin platform QRX009 in the second half of the year. » Więcej na de.investing.com

Quoin will test its topical rapamycin product QRX009 in multiple investigator-led clinical trials for rare diseases, starting with a pachyonychia congenita study under Prof. Edel O’Toole in Q3. Additional studies for Gorlin syndrome and tuberous sclerosis are planned for 2026, and the company aims to file INDs for further indications in Q2/Q3 2026. The stock is trading near its 52-week low with a market cap of about $9.85 million; the balance sheet shows a current ratio of 3.61 and more cash than debt. » Więcej na de.investing.com

Quoin Pharmaceuticals' stock jumped 66% premarket after the company announced it had achieved target rapamycin concentrations for a topical formulation (4% w/w) and a skin patch (5% w/w). Quoin plans to manufacture clinical and stability batches for at least one technology later this quarter and aims to begin clinical trials in the first half of 2026. Initial indications targeted are microcystic lymphatic malformations and venous malformations; the pipeline also includes programs for Netherton syndrome and peeling skin syndrome. A recently completed capital raise is intended to finance the Netherton studies and other programs. » Więcej na de.investing.com