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Santhera: phase‑1 topline for AGAMREE® shows glucocorticoid activity without meaningful immunosuppression
Santhera reports topline results from a Phase‑1 study of AGAMREE® conducted by Catalyst, which show glucocorticoid and anti‑inflammatory effects at clinical doses but only minor immunosuppressive biomarker effects. Relevant immunosuppressive effects were observed only at doses above the currently approved AGAMREE dosage. Catalyst holds North American rights for DMD and potential follow‑on indications; Santhera retains pre‑negotiation rights outside North America and is entitled to sales‑based milestones and royalties. » Mere på finanzen.net
Santhera reports 98% revenue growth in 2025 driven by AGAMREE
Santhera recorded a 98% increase in total revenue in 2025 to CHF 77.4 million, driven by strong uptake of AGAMREE in Europe and the US as well as license and milestone receipts. Product sales rose to CHF 25.8 million and license and milestone payments to CHF 23.1 million; Catalyst paid a milestone of USD 12.5 million after US sales exceeded USD 100 million. After year-end, Santhera signed an exclusive license agreement with Nxera worth up to USD 205 million, which included an upfront payment of USD 40 million. Cash and cash equivalents amounted to CHF 22.4 million as of 31.12.2025 (excluding the Nxera upfront), and the company expects cash-flow break-even in Q3 2026 without additional financing. » Mere på finanzen.net
Santhera appoints Marc Clausse as chief commercial officer
Santhera Pharmaceuticals has appointed Marc Clausse as chief commercial officer (CCO). Clausse will assume responsibility for leading the company’s commercial activities. » Mere på finanzen.net
Virksomhedstal
| (EUR) | juni 2026 | YoY |
|---|---|---|
| Omsætning | 52,36 mio. | - |
| Bruttofortjeneste | 19,44 mio. | - |
| Nettoresultat | -23,32 mio. | - |
| EBITDA | -4,16 mio. | - |
Fundamentale data
| Nøgletal | Værdi |
|---|---|
Markedsværdi | 260,24 mio. € |
Antal aktier | 15,3 mio. |
Højeste/laveste i 52 uger | 20,11 € - 6,66 € |
| Udbytte | Nej |
Beta | -0,28 |
P/E (PE Ratio) | -7,00 |
PEG (PEG Ratio) | -0,09 |
K/I (PB Ratio) | -37,10 |
P/S (PS Ratio) | 2,41 |
Virksomhedsprofil
Santhera Pharmaceuticals Holding AG, et specialiseret lægemiddelselskab, udvikler og kommercialiserer sammen med sine datterselskaber lægemidler til sjældne neuromuskulære og pulmonale sygdomme med høj uopfyldt medicinsk behov i EU og internationalt. Selskabets vigtigste kandidat i pipelinen er vamorolone, som udvikles til behandling af Duchennes muskeldystrofi (DMD). Dets pipeline på klinisk stadie omfatter også lonodelestat (POL6014) til behandling af cystisk fibrose og andre neutrofile pulmonale sygdomme samt omigapil, som behandler medfødte muskeldystrofier. Selskabet udlicenserer desuden rettighederne uden for Nordamerika og Frankrig til sit godkendte produkt Raxone (idebenone) til behandling af Lebers hereditære optikusneuropati. Santhera Pharmaceuticals Holding AG blev grundlagt i 2004 og har hovedkvarter i Pratteln, Schweiz.
| Navn | Santhera Pharma Aktie |
| CEO | Orlando Oliveira |
| Hjemsted | Pratteln,
bl Schweiz |
| Websted | |
| Sektor | Sundhed |
| Branche | Lægemidler |
| Børsnotering | 06.03.2014 |
| Medarbejdere | 78 |
Tickersymboler
| Børs | Symbol |
|---|---|
SIX | SANN.SW |
London Stock Exchange | 0QN1.L |
Pnk | SPHDF |
London | 0QN1.L |
