Jaguar Health

Jaguar Health has introduced Neonorm Dog, an over-the-counter plant-based product to support stool consistency and fluid balance in dogs’ gastrointestinal tract. The formulation contains a standardized extract from the Croton lechleri tree and complements the existing Neonorm line for foals and calves. Neonorm Dog will be sold through selected online and specialty channels such as Amazon and Chewy and is intended as an alternative to home remedies, not a replacement for veterinary care. » Plus sur de.investing.com

Jaguar Health reported data on liquid oral crofelemer in pediatric patients with intestinal failure showing a reduced need for parenteral support. In one patient with MVID, the weekly weight‑normalized requirement decreased by up to 48% after more than 12 months; two children with short bowel syndrome showed reductions of up to 40%. The treatment was well tolerated. The company intends to seek Breakthrough Therapy designation for crofelemer in MVID and plans an FDA approval submission in mid‑2027. » Plus sur de.investing.com

Jaguar Health reports that a coca leaf extract developed by Magdalena Biosciences prevented weight gain in mice on a high‑fat diet in a preclinical study at the University of Calgary without reducing food intake or activity. Magdalena Biosciences, a joint venture of Jaguar and Filament Health, is developing the extract as a prescription candidate to prevent weight regain after stopping GLP‑1 medications, in line with FDA botanical guidance. The study was supported by ENACO‑compliant coca leaves, and One Small Planet is providing funding of US$1 million. Jaguar is meanwhile under substantial financial pressure; the stock trades near its 52‑week low and the company shows a sharp share price decline and rapid cash burn. » Plus sur de.investing.com