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O preço-alvo médio dos analistas é € 66,97 (+135,40%). A mediana é € 66,97 (+135,40%).

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Maze Therapeutics: pipeline with MZE829 and MZE782 faces pivotal clinical data

Maze Therapeutics reported at the H.C. Wainwright conference progress on the APOL1 inhibitor MZE829 (Phase II HORIZON) and the PKU candidate MZE782. The company expects final HORIZON data by end‑2024/early‑2025 and plans to launch a registration‑enabling MZE829 program in H1 2025; a Phase II start for MZE782 in CKD is also planned for H1 2025, with top‑line PKU data expected in 2027. Early data show an average UACR reduction of 36% (50% responder rate) for MZE829 and a 42‑fold increase in urinary Phe excretion with MZE782; further development steps will depend largely on upcoming data, biomarker analyses and PARSOL‑Shield recommendations. » Mais em de.investing.com
Maze Therapeutics shows encouraging early data for MZE829 and MZE782, pivotal tests still pending

Maze Therapeutics presented early clinical signals at the Citigroup Biopharma Summit: the lead APOL1 program MZE829 showed a mean UACR reduction of 36% in 12 evaluable patients, with particularly strong effects in the FSGS subgroup. The PKU program MZE782 recorded a 42-fold increase in urinary phenylalanine excretion in Phase I and is already in Phase II. Management emphasized that key approval decisions, study-design discussions with the FDA and final HORIZON data are still outstanding; financial figures were not disclosed. » Mais em de.investing.com
Maze Therapeutics appoints Dr. Paula Johnson and Dr. Sophie Kornowski to the board

Maze Therapeutics has appointed Dr. med. Paula Johnson and Dr. pharm. Sophie Kornowski to its board of directors. Johnson brings more than 30 years of experience in clinical cardiology and research as well as leadership roles in academia and oversight bodies; Kornowski has over 35 years of executive experience in the biopharma industry, most recently as CEO of Boston Pharmaceuticals. The clinical biopharma company develops small‑molecule precision medicines for kidney and metabolic diseases and expects additional data on MZE829 in late 2026/early 2027 as well as initial data on MZE782 in 2027. » Mais em de.investing.com

Dados financeiros da empresa

No último trimestre, Maze Therapeutics registou receitas de € 0 e um ganho líquido de -€ 39,19 mi

(EUR)	junho de 2026	YoY
Receitas	0	-
Ganho bruto	0	100,00%
Ganho líquido	-39,19 mi	37,15%
EBITDA	-38,03 mi	35,72%

Dados fundamentais

Métrica	Valor
Capitalização bolsista	€ 1,58 bi
Número de ações	55,55 mi
Máximo/mínimo de 52 semanas	€ 47,90 - € 19,60
Dividendos	Não
Beta	2,15
PER (PE Ratio)	-11,66
PEG (PEG Ratio)	0,22
P/VC (PB Ratio)	4,16
P/V (PS Ratio)	88,74

Perfil da empresa

Maze Therapeutics, Inc. ist ein biopharmazeutisches Unternehmen in der klinischen Phase und entwickelt niedermolekulare Präzisionsarzneimittel für die Behandlung von Nieren-, Herz-Kreislauf- und verwandten Stoffwechselkrankheiten sowie von Fettleibigkeit in den Vereinigten Staaten. Zu seinen führenden Programmen gehören MZE829, ein oraler niedermolekularer Inhibitor von Apolipoprotein L1, der sich in der klinischen Phase II zur Behandlung von Patienten mit APOL1-Nierenerkrankung befindet, und MZE782, ein oraler niedermolekularer Inhibitor des Solute-Transporters SLC6A19, der sich in der klinischen Phase I zur Behandlung von chronischen Nierenerkrankungen befindet. Maze Therapeutics, Inc. war früher als Modulus Therapeutics, Inc. bekannt und änderte im September 2018 seinen Namen in Maze Therapeutics, Inc. Das Unternehmen wurde im Jahr 2017 gegründet und hat seinen Sitz in South San Francisco, Kalifornien.