Zealand Pharma Aktie

Zealand Pharma has sold its economic rights to Rusfertide to Royalty Pharma for $100 million. The payment is made in two tranches: $50 million at closing and $50 million on the first anniversary; the transaction is complete. Zealand retains a residual royalty of 0.25% on annual worldwide net sales above $1.5 billion, and Royalty Pharma receives 0.75% above that threshold. The FDA has set a target date for the approval application in the third quarter of 2026, and Takeda will take over worldwide commercialization. » More on de.investing.com

Jefferies downgraded Zealand Pharma from "Buy" to "Hold" and cut the price target from 505 DKK to 320 DKK, a decline of about 37%. The analyst house cited a lack of near‑term catalysts and reduced the success probability for survodutide from 60% to 40% due to ongoing tolerability concerns after Phase III data. With no company‑specific news, the downgrade was the main driver of the share drop; a short‑term recovery now depends largely on progress with petrelintide. » More on de.investing.com

Zealand Pharma's shares rose about 6.8% today, partially reversing a more than 24% decline after negative study results. The Phase‑III trial of Survodutid showed high discontinuation rates due to gastrointestinal side effects, and Phase‑II data for Petrelintid showed only around 9% placebo‑adjusted weight loss, prompting Barclays to voice safety concerns. The stabilization today is attributed to the announced appearance of the CEO at the Goldman Sachs conference and an ongoing share buyback program (up to DKK 1.3bn). A fundamental turnaround in the clinical outlook is not signaled; the stock remains well below its 52‑week high. » More on de.investing.com